Author(s): Kopanakis N.; Vassiliadou D.; Sidera C.; Efstathiou E.; Spiliotis J.; Argyriou E.-O.; Chionis M.; Kyriazanos J.
Source: Journal of B.U.ON.; 2018; vol. 23 (no. 2); p. 488-493
Publication Date: 2018
Publication Type(s): Article
Abstract:Purpose: Cytoreductive surgery (CRS) plus hyperthermic intraperitoneal chemotherapy (HIPEC) has become a crucial method in the management of peritoneal metastasis. This study evaluated the Quality of Life (QoL) post CRS plus HIPEC. Methods: 80/95 patients underwent CRS plus HIPEC at the Metaxa Cancer Hospital, Piraeus, Greece from 06/2011 to 06/2015 and completed the colorectal version of the Functional Assessment of Cancer Therapy questionnaire (FACT-C, version 4) at 1 week pre-operatively and at 1, 3, 6, 12, 18, 24 months post-operatively. The subscales assessed were the physical, social/family, emotional and functional well-being. Results: In all subscales, fluctuations in the scores indicated a worsening of QoL in the first 3 post-operative months, followed by improvement back to pre-operative levels and even better scores later on. Statistical improvement was proven for the physical and emotional well-being subscales. Conclusions: The significant improvement in the physical well-being is attributed to the eradication of symptoms, whereas the relevant improvements in the emotional well-being subscale are explained both by the pre-operative desperation of the diagnosis or relapse of malignancy, and the post-operative hopefulness after a successful operation.
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Database: EMBASE