Author(s): Zaben M.; Jamjoom A.; Poon M.; Brennan P.; Ahmed A.; Chari A.; Kitchen J.; Kolias A.

Source: British Journal of Neurosurgery; 2017; vol. 31 (no. 3); p. 387

Publication Date: 2017

Publication Type(s): Conference Abstract

Available in full text at British Journal of Neurosurgery –  from Informa Healthcare

Abstract:Aim: To establish contemporary practice patterns and the infection rate of External Ventricular Drainage (EVD) in the UK and Ireland. Method: Clinical variables were prospectively collected over a 6-month period on patients who have an EVD inserted in 21 participating units. The primary outcome measure was 30-day EVD-related infection (ERI). A Cox Regression Model was used for multivariate analysis. Result: A total of 495 EVD catheters were inserted into 357 patients equating to 4626 drainage days. Of the catheters, 188 (38%) were antibiotic-impregnated, 161 (32%) were non-impregnated and 146 (30%) were silver-impregnated catheters. A total of 45 ERIs occurred giving the cohort an infection rate of 9% or 0.97 infections per 100-drainage days. Multivariate analysis adjusted for age and sex showed that EVD duration of >=8 days had a significantly higher risk of ERI [HR=2.47(1.12-5.45); p=.02] compared to catheters in-situ =8 days have a higher risk of infection.

Database: EMBASE