Author(s): Allard M.A.; Adam R.; Giuliante F.; Lapointe R.; Hubert C.; Ijzermans J.N.M.; Mirza D.F.; Elias D.; Laurent C.; Gruenberger T.; Poston G.; Letoublon C.; Isoniemi H.; Lucidi V.; Popescu I.; Figueras J.

Source: British Journal of Cancer; Aug 2017; vol. 117 (no. 5); p. 604-611

Publication Date: Aug 2017

Publication Type(s): Article

Available in full text at British Journal of Cancer –  from National Library of Medicine

Abstract:Although the number of colorectal liver metastases (CLM) is decreasingly considered as a contraindication to surgery, patients with 10 CLM or more are often denied liver surgery. This study aimed to evaluate the outcome after liver surgery and to identify prognostic factors of survival in such patients.Methods:The study population consisted of a multicentre cohort of patients with CLM (N=12 406) operated on, with intention to resect, from January 2005-June 2013 and whose data were prospectively collected in the LiverMetSurvey registry.Results:Overall, the group a(c) 3/410 CLM (N=529, 4.3%) experienced a 5-year overall survival (OS) of 30%. A macroscopically complete (R0/R1) resection (72.8% of patients) was associated with a 3- A nd 5-year OS of 61% and 39% vs 29% and 5% for R2/no resection patients

Copyright © 2017 Cancer Research UK.

Database: EMBASE

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